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AlphaMedEdu

Bone and soft tissue Case 2. Skull base mass from a 5 YO patient.


Focal positivity for cytokeratin, brachyury, S100, SMA

INI1/SMARCB1 loss on immunohistochemical stain as well as SMARCB1 deletion on NGS

Diagnosed as poorly diff chordoma, but malignant rhabdoid tumor cannot be ruled out.

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