AlphaMedEdu Blog | Page 15 of 15

AlphaMedEdu

Feb 21 min read

GYN Case 1. Endometrial curretage from a 40 year old patient.

•Diagnosis: epithelioid trophoblastic tumor (ETT) •ETT is a malignant neoplasm of chorionic-type intermediate trophoblast •The rarest of...

AlphaMedEdu

Feb 11 min read

ENT case 4. Sinonasal mass from a middle-aged patient

Diffusely positive for both squamous and neuroendocrine markers. SMARCB1-deficient sinonasal carcinoma •Rare, high grade aggressive...

AlphaMedEdu

Jan 311 min read

Bone and soft tissue Case 4. Lytic bone lesion from a pediatric patient.

•Diagnosis: Langerhans cell histiocytosis •Majority of cases have MAPK pathway gene mutations, with BRAFp.V600E being the most prevalent.

AlphaMedEdu

Jan 311 min read

Bone and soft tissue Case 3. Painful knee mass from a middle-aged patient.

•Diagnosis: epithelioid hemangioendothelioma (EHE) •Great variability in clinical behavior and prognosis, occurs in patients of wide age...

AlphaMedEdu

Jan 311 min read

Bone and soft tissue Case 2. Skull base mass from a 5 YO patient.

•Focal positivity for cytokeratin, brachyury, S100, SMA •INI1/SMARCB1 loss on immunohistochemical stain as well as SMARCB1 deletion on...

AlphaMedEdu

Jan 311 min read

Bone and soft tissue case 1. Skull base mass.

•Diagnosis: chordoma •Clinical: most commonly presents as lytic, destructive bone lesion in the axial skeleton: base of the skull, spine,...

AlphaMedEdu

Jan 311 min read

ENT case 3. Thyroid mass.

•Diagnosis: high grade follicular cell-derived non-anaplastic thyroid carcinoma, aka: poorly differentiated thyroid carcinoma •In the...

AlphaMedEdu

Jan 301 min read

ENT case 2: buccal mucosa mass from a 19 YO patient

•Diagnosis: extraosseous/peripheral ameloblastoma •10% of all amelob;astomas, occur in wide age range 9-92 •Molecular changes: similar to...

AlphaMedEdu

Jan 301 min read

ENT Case 1

•Diagnosis: Medullary carcinoma of thyroid •2% of thyroid malignancies, and 8% of thyroid cancer-related deaths •25% of MTCs are...